62 INCIIEICB OF AUTOANTIBODIES IF NOBMAL CHILDREN

Autoantibodies frequency in children with visceral leishmaniosis

Introduction The visceral leishmaniosis (VL), or Calazar, is a chronic severe systemic disease, potentially fatal to humans. Currently, VL is the prototype of a specific immune dysfunction resulting from parasitism of leishmania donovani in macrophages, producing a broad spectrum of clinical and immunological reversible only with specific treatment. Serum Analysis from infected adult patients d...

Autoantibodies as markers of beta-cell autoimmunity in children

Type 1 diabetes (T1D) is a chronic disease caused by destruction of the insulin producing beta-cells in the pancreas. The incidence of T1D has increased rapidly, especially in the Western world and among young children. The pathogenesis of T1D is not fully understood, but the beta-cells are believed to be destroyed by an autoimmune process initiated years before the onset of T1D. During this pr...

Chapter 62

The study highlights a deeper insight of the genes involved in the degradation of diverse number of refractory environmental pollutants, the pool of available genomic data needs to be enhanced. There seems to be a high urgency for such ecologically important microbes to be sequenced and their genomes to be critically analyzed. Sphingobium indicum B90A is the most efficient degrader of Hexachlor...

فهرست شماره 62

Screening for autoantibodies in children with opsoclonus-myoclonus-ataxia.

Various paraneoplastic autoantibodies have been linked to discrete neurologic syndromes and tumors in adults, but little is known about their incidence in children. We report a cross-sectional study of known paraneoplastic antibodies in 59 children with opsoclonus-myoclonus-ataxia, 86% of whom were moderately or severely symptomatic, and 68% of whom had relapsed at the time of testing. This tot...